Thousands of People all over the world are suffering from
Post-SSRI Sexual Dysfunction
Research Updates: 2025
We are pleased to announce the launch of our new research initiative, in collaboration with leading experts in their fields.
PSSD Research Grant Opportunity
Applicants from all disciplines are eligible including but not limited to graduate students (Master’s, PhD), postdoctoral fellows within the first two years of their fellowship, clinical fellows, residents and medical students from Faculties of Medicine.
Applicants must:
- be in Canada
- be registered students at a Canadian university
- have an academic supervisor at a Canadian university available to supervise
Three grants, each valued at $10,000 CAD, will be awarded for PSSD research.
Applications due: June 30th 2025.12-month project timeline.Scientific Research:
The PSSD Network strives to provide support and funding for scientific research on Post-SSRI Syndrome/Post-SSRI Sexual Dysfunction, with the ultimate goal of discovering a cure or effective treatments for affected patients.
Presently we are actively supporting the research conducted by Dr. Melcangi et al. at the University of Milan. Additionally, as of February 2025, we are expanding our support to include the research of Dr. Ashley Monks at the University of Toronto, and Dr. Antonei Csoka at Howard University, Washington D.C.
Post-SSRI Sexual Dysfunction
A subset of people experience a debilitating condition known as Post-SSRI Sexual Dysfunction (PSSD) following the use of SSRIs, SNRIs and other SRI medications.
Common symptoms include, but are not limited to: genital numbness, a complete loss of libido, erectile dysfunction, vaginal dryness, cognitive impairment, anhedonia and emotional blunting.
Our explainer video delves into the substantial and enduring effects of this condition, as well as its impact on those who are afflicted.
PSSD in the Media:
What the Experts are Saying:
DR. ROBERTO COSIMO MELCANGI
Professor in Endocrinology
“Despite the current efforts, more work is still needed to advance the understanding of PSSD in terms of diagnostic markers and therapeutic strategies.”
— Private Email, December 28, 2023
Dr. Antonei Csoka
Biogerontologist, Associate Professor in the Department of Anatomy at Howard University
“Post-SSRI Sexual Dysfunction (PSSD) and related disorders such as PFS likely represent types of iatrogenic epigenetic damage previously unseen in human history. On the individual level the consequences are catastrophic, and there may be population-level effects as well. Increasing our knowledge and understanding of these increasingly-prevalent disorders is paramount.”
— Private Email, Sep 2, 2023
Dr. Josef Witt-doering
Psychiatrist, Global Pharmacovigilance Medical Director and former FDA Medical officer
“Once PSSD symptoms begin they can last for years and may even be permanent in some people.” … “Despite the public recognition of this condition by major government health authorities, the condition is still underrecognized by the medical community.”
— What is PSSD and Why is No One Talking About it?, Jan 10, 2023
Resources & Support
Help, support, and resources are available to help you or a loved one cope with the effects of Post-SSRI Sexual Dysfunction.
Additional Resources
SIDE FX HUB
“SIDEfxHUB is a charity dedicated to bringing together those affected by Post-Finasteride Syndrome (PFS) and Post-SSRI Sexual Dysfunction (PSSD). We focus on raising awareness, promoting recognition, and supporting research into finding treatments for these conditions.”
Surviving Antidepressants
“SurvivingAntidepressants.org is a site for peer support, documentation, and education regarding tapering and withdrawal syndrome from psychiatric drugs, including antidepressants.”
Inner Compass Initiative - ICI
“Inner Compass Initiative is dedicated to helping people make more informed choices about taking and withdrawing from psychiatric medications.”
Antidepressant Risks
“We are a team of experts with the goal of helping people understand the risks of taking antidepressants. Antidepressants have helped many with the debilitating symptoms of depression, anxiety and other conditions. They can also have dangerous and life-threatening side-effects”.
RxISK
“RxISK is a free, independent drug safety website to help you weigh the benefits of any medication against its potential dangers.”
PSSD Hilfe Deutschland e.V.
“Our interest is not in enforcing our assumption, but rather in the unbiased, scientific, and above all open-ended examination of possible causes. Additionally, we aim to raise awareness of existing symptoms and encourage qualified individuals to engage with the topic from a scientific perspective.”
SHAPE - Sexual Health & Genito-Pelvic Pain Knowledge Empowerment Hub -
“The Sexual Health And genito-Pelvic pain knowledge Empowerment Hub (SHAPE) is a pan-Canadian initiative dedicated to addressing the barriers to evidence-based information and treatment for sexual difficulties and genito-pelvic pain that affect the lives of countless individuals, especially women and gender-diverse people.”